Module Number

BIOINF4110 (entspricht BIO-4110) 		Module Title

Sequence Bioinformatics 		Lecture Type(s)

Lecture, Tutorial
ECTS 9
Work load
- Contact time
- Self study
Workload:
270 h
Class time:
90 h / 6 SWS
Self study:
180 h
Duration 1 Semester
Frequency In the winter semester
Language of instruction English
Type of Exam

Written or oral exam
Content

This course covers sequence-based bioinformatics and evolution. The main topics
are pairwise alignment, BLAST and related heuristics, suffix trees and
their applications, sequence assembly, multiple alignment, hidden Markov models,
gene finding, motif finding, machine learning methods, models of DNA
evolution, phylogeny, whole genome phylogeny, computational methods in genomics,
and metagenomics.
Objectives

The first aim of this course is to introduce students to advanced concepts and
methods in bioinformatics, focusing on algorithmic, computational and mathematical
aspects. The second aim of this course is to enable students to apply
advanced methods to problems in molecular biology and related fields. After taking
this class, students will have a good understanding of the most important
approaches in sequence-based bioinformatics, will know which problems can be
addressed by the methods and will know how to apply such methods.
Allocation of credits / grading
Type of Class
Status
SWS
Credits
Type of Exam
Exam duration
Evaluation
Calculation
of Module (%)
Lecture
V
o
4
6.0
wt
90
g
100
Tutorial
Ü
o
2
3.0
Prerequisite for participation There are no specific prerequisites.
Lecturer / Other Huson
Literature

Lecture notes and scientific publications
Last offered unknown
Planned for currently not planned
Assigned Study Areas BIO-SEQ, INFO-INFO, MEDI-APPL, MEDI-INFO, MEDZ-BIOINFO, MEDZ-RES, ML-CS