Oral exam or, in case of too many students, written exam. 50% of the achievable points from the assignments and the project, individually, are required for exam admission. Points achieved in excess of 50% serve as a bonus for the final exam.

The lecture will focus on RNA structure and structure prediction, protein structures and their modeling, protein structure prediction, methods and concepts of systems biology, algorithms for the analysis of expression data and biological networks (concepts, inference, simulation). The lecture goes into more depth on the topics already included in the BSc module 'Fundamentals of Bioinformatics', covering in particular advanced techniques and research-related applications. Project work on research-related topics is embedded in the lecture.

Students can abstract and formalise structural and systems biology problems. They know competent applications of common procedures and tools of structural and systems bioinformatics and can apply them to biological data. They have strengthened their language competence (English) in listening comprehension, writing and presentation.

Folien zur Vorlesung
Branden, Tooze: Introduction to Protein Structure, Garland Science, 1998
Andrew Leach: Molecular Modeling. Principles and Applications,
Prentice Hall, 2nd ed., 2001